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COVER: ST2825 specifically inhibits IL-1 induction of NF-κ -regulated reporter gene in HeLa cells: (A) schematic representation of the structure of ST2825; (B) superimposition of the structure of ST2825 and the heptapeptide RDLVPGT in the BB loop of MyD88. For more information, see Loiarro et al., "Inhibition of MyD88 dimerization and of recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound," pages 801-810. Pictured is corresponding author, Claudio Sette.