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₆₁, the principal leukocyte receptor for laminin, plays an important role in neutrophil transmigration. Expression of ₆ integrins on transmigrated neutrophils, induced by IL-1 and TNF (left and right panels, respectively) in the cremaster muscle suggest that, unlike IL-1, TNF--induced transmigration does not regulate neutrophil cell surface expression of this integrin. For more information, see Dangefield et al., pages 159-165.