Journal of Leukocyte Biology, Vol 55, Issue 3 410-422, Copyright © 1994 by Society for Leukocyte Biology
JOURNAL ARTICLE |
C Sunderkotter, K Steinbrink, M Goebeler, R Bhardwaj and C Sorg
Department of Dermatology, University of Munster, Germany.
Macrophages are supposed to play a key role in inflammatory and tumor angiogenesis. Their importance derives from (1) their ubiquitous presence in normal and especially inflamed tissues, (2) their potential to become activated in response to appropriate stimuli, and (3) their repertoire of secretory products. By release of proteases, growth factors (bFGF, GM-CSF, TGF-alpha, IGF-I, PDGF, VEGF/VPF, TGF-beta), and other monokines (IL-1, IL-6, IL-8, TNF-alpha, substance P, prostaglandins, interferons, thrombospondin 1), activated macrophages have the capability to influence each phase of the angiogenic process, such as alterations of the local extracellular matrix, induction of endothelial cells to migrate or proliferate, and inhibition of vascular growth with formation of differentiated capillaries. This review describes macrophage physiology and the influence of macrophage secretory products on the different phases of angiogenesis in vitro and in vivo.
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 C. Goepfert, C. Sundberg, J. Sevigny, K. Enjyoji, T. Hoshi, E. Csizmadia, and S. Robson Disordered Cellular Migration and Angiogenesis in cd39-Null Mice Circulation, December 18, 2001; 104(25): 3109 - 3115. [Abstract] [Full Text] [PDF]
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 R. T. Palframan, S. Jung, G. Cheng, W. Weninger, Y. Luo, M. Dorf, D. R. Littman, B. J. Rollins, H. Zweerink, A. Rot, et al. Inflammatory Chemokine Transport and Presentation in HEV: A Remote Control Mechanism for Monocyte Recruitment to Lymph Nodes in Inflamed Tissues J. Exp. Med., November 5, 2001; 194(9): 1361 - 1374. [Abstract] [Full Text] [PDF]
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R. S. Kellar, L. K. Landeen, B. R. Shepherd, G. K. Naughton, A. Ratcliffe, and S. K. Williams Scaffold-Based Three-Dimensional Human Fibroblast Culture Provides a Structural Matrix That Supports Angiogenesis in Infarcted Heart Tissue Circulation, October 23, 2001; 104(17): 2063 - 2068. [Abstract] [Full Text] [PDF]
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A. Obana, Y. Gohto, K. Kaneda, S. Nakajima, and T. Miki PDT to Monkey CNV with ATX-S10(Na): Inappropriateness of Early Laser Irradiation for Selective Occlusion Invest. Ophthalmol. Vis. Sci., October 1, 2001; 42(11): 2639 - 2645. [Abstract] [Full Text] [PDF]
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I. HARTLAPP, R. ABE, R. W. SAEED, T. PENG, W. VOELTER, R. BUCALA, and C. N. METZ Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo FASEB J, October 1, 2001; 15(12): 2215 - 2224. [Abstract] [Full Text] [PDF]
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Q. E. H. Low, I. A. Drugea, L. A. Duffner, D. G. Quinn, D. N. Cook, B. J. Rollins, E. J. Kovacs, and L. A. DiPietro Wound Healing in MIP-1{alpha}-/- and MCP-1-/- Mice Am. J. Pathol., August 1, 2001; 159(2): 457 - 463. [Abstract] [Full Text]
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D. Zagury, A. Burny, and R. C. Gallo Toward a new generation of vaccines: The anti-cytokine therapeutic vaccines PNAS, July 3, 2001; 98(14): 8024 - 8029. [Abstract] [Full Text] [PDF]
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D.-H. KANG, A. H. JOLY, S.-W. OH, C. HUGO, D. KERJASCHKI, K. L. GORDON, M. MAZZALI, J. A. JEFFERSON, J. HUGHES, K. M. MADSEN, et al. Impaired Angiogenesis in the Remnant Kidney Model: I. Potential Role of Vascular Endothelial Growth Factor and Thrombospondin-1 J. Am. Soc. Nephrol., July 1, 2001; 12(7): 1434 - 1447. [Abstract] [Full Text] [PDF]
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T. Mäkitie, P. Summanen, A. Tarkkanen, and T. Kivelä Tumor-Infiltrating Macrophages (CD68+ Cells) and Prognosis in Malignant Uveal Melanoma Invest. Ophthalmol. Vis. Sci., June 1, 2001; 42(7): 1414 - 1421. [Abstract] [Full Text]
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M. Nesbit, H. Schaider, T. H. Miller, and M. Herlyn Low-Level Monocyte Chemoattractant Protein-1 Stimulation of Monocytes Leads to Tumor Formation in Nontumorigenic Melanoma Cells J. Immunol., June 1, 2001; 166(11): 6483 - 6490. [Abstract] [Full Text] [PDF]
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 D. W. Scruggs and S. D. Sorden Proliferative Vasculopathy and Cutaneous Hemorrhages in Porcine Neonates Infected with the Porcine Reproductive and Respiratory Syndrome Virus Vet. Pathol., May 1, 2001; 38(3): 339 - 342. [Abstract] [Full Text] [PDF]
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E. R. Fedyk, D. Jones, H. O. D. Critchley, R. P. Phipps, T. M. Blieden, and T. A. Springer Expression of Stromal-Derived Factor-1 Is Decreased by IL-1 and TNF and in Dermal Wound Healing J. Immunol., May 1, 2001; 166(9): 5749 - 5754. [Abstract] [Full Text] [PDF]
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R. Gillitzer and M. Goebeler Chemokines in cutaneous wound healing J. Leukoc. Biol., April 1, 2001; 69(4): 513 - 521. [Abstract] [Full Text]
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E. Y. Lin, A. V. Nguyen, R. G. Russell, and J. W. Pollard Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to Malignancy J. Exp. Med., March 19, 2001; 193(6): 727 - 740. [Abstract] [Full Text] [PDF]
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W. T. Bellamy, L. Richter, D. Sirjani, C. Roxas, B. Glinsmann-Gibson, Y. Frutiger, T. M. Grogan, and A. F. List Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes Blood, March 1, 2001; 97(5): 1427 - 1434. [Abstract] [Full Text] [PDF]
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 B. Moller, C. Rasmussen, B. Lindblom, and M. Olovsson Expression of the angiogenic growth factors VEGF, FGF-2, EGF and their receptors in normal human endometrium during the menstrual cycle Mol. Hum. Reprod., January 1, 2001; 7(1): 65 - 72. [Abstract] [Full Text] [PDF]
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H. Goto, K. Kohno, S. Sone, S.-i. Akiyama, M. Kuwano, and M. Ono Interferon {{gamma}}-dependent Induction of Thymidine Phosphorylase/Platelet-derived Endothelial Growth Factor through {{gamma}}-Activated Sequence-like Element in Human Macrophages Cancer Res., January 1, 2001; 61(2): 469 - 473. [Abstract] [Full Text]
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 Y. Han, T. Tuan, H Wu, M Hughes, and W. Garner TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP J. Cell Sci., January 1, 2001; 114(1): 131 - 139. [Abstract] [PDF]
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G. Bernardini, G. Spinetti, D. Ribatti, G. Camarda, L. Morbidelli, M. Ziche, A. Santoni, M. C. Capogrossi, and M. Napolitano I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo Blood, December 15, 2000; 96(13): 4039 - 4045. [Abstract] [Full Text] [PDF]
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B. Bussolati, L. Biancone, P. Cassoni, S. Russo, M. Rola-Pleszczynski, G. Montrucchio, and G. Camussi PAF Produced by Human Breast Cancer Cells Promotes Migration and Proliferation of Tumor Cells and Neo-Angiogenesis Am. J. Pathol., November 1, 2000; 157(5): 1713 - 1725. [Abstract] [Full Text] [PDF]
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S. Shimura, G. Yang, S. Ebara, T. M. Wheeler, A. Frolov, and T. C. Thompson Reduced Infiltration of Tumor-associated Macrophages in Human Prostate Cancer: Association with Cancer Progression Cancer Res., October 1, 2000; 60(20): 5857 - 5861. [Abstract] [Full Text]
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L. Cervenak, L. Morbidelli, D. Donati, S. Donnini, T. Kambayashi, J. L. Wilson, H. Axelson, E. Castanos-Velez, H.-G. Ljunggren, R. D. W. Malefyt, et al. Abolished angiogenicity and tumorigenicity of Burkitt lymphoma by interleukin-10 Blood, October 1, 2000; 96(7): 2568 - 2573. [Abstract] [Full Text] [PDF]
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 C. Willam, P. Koehne, J. S. Jurgensen, M. Grafe, K. D. Wagner, S. Bachmann, U. Frei, and K.-U. Eckardt Tie2 Receptor Expression Is Stimulated by Hypoxia and Proinflammatory Cytokines in Human Endothelial Cells Circ. Res., September 1, 2000; 87(5): 370 - 377. [Abstract] [Full Text] [PDF]
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J.-i. Fukushi, M. Ono, W. Morikawa, Y. Iwamoto, and M. Kuwano The Activity of Soluble VCAM-1 in Angiogenesis Stimulated by IL-4 and IL-13 J. Immunol., September 1, 2000; 165(5): 2818 - 2823. [Abstract] [Full Text] [PDF]
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W. Philipp, L. Speicher, and C. Humpel Expression of Vascular Endothelial Growth Factor and Its Receptors in Inflamed and Vascularized Human Corneas Invest. Ophthalmol. Vis. Sci., August 1, 2000; 41(9): 2514 - 2522. [Abstract] [Full Text]
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T. Ueno, M. Toi, H. Saji, M. Muta, H. Bando, K. Kuroi, M. Koike, H. Inadera, and K. Matsushima Significance of Macrophage Chemoattractant Protein-1 in Macrophage Recruitment, Angiogenesis, and Survival in Human Breast Cancer Clin. Cancer Res., August 1, 2000; 6(8): 3282 - 3289. [Abstract] [Full Text]
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 M. Slevin, J. Krupinski, A. Slowik, P. Kumar, A. Szczudlik, and J. Gaffney Serial Measurement of Vascular Endothelial Growth Factor and Transforming Growth Factor-{beta}1 in Serum of Patients With Acute Ischemic Stroke Stroke, August 1, 2000; 31(8): 1863 - 1870. [Abstract] [Full Text] [PDF]
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 S. C Pearce, O. Hudlicka, and M. D Brown Effect of indomethacin on capillary growth and microvasculature in chronically stimulated rat skeletal muscles J. Physiol., July 15, 2000; 526(2): 435 - 443. [Abstract] [Full Text] [PDF]
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